Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Country's biggest stars gathered in Las Vegas on Sunday for the 2013 Academy of Country Music Awards.
Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
n. 沼地，极多，回转 n. 大量，许多 v. 使转，扭
Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities
Soft matter science and the COVID-19 pandemic
"Martial arts are highlighted in the TV series. The actors performed real kung fu," a Douban user Weishenmeyaoxuefa said.
Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
James Bond Themes 1. "Goldfinger" by Shirley Bassey
It plans to help at least 130,000 rural people cast off poverty and relocate 163,000 residents in 2017.
Trends and targets in antiviral phototherapy
Lady Gaga以5.9千万位列第四，其后是5.45千万的碧昂斯。前者在统计期间演出了66场，也靠与范思哲和MAC的合约获得收入，同时还有她自己的黑色香水。后者与其老公Jay Z的On The Run巡回演唱会通过19天（北美日期），赚得了超过10千万，创造了能与滚石相比较的第一对音乐界夫妻档夜平均的神话。
But I don't think you can say that to us anymore. Are we even on your list of priorities? My father always says "You are what you do, not what you say." 但我不能再相信这样的话了，孩子们还是你们的优选名单吗？我爸爸总是说：“听其言，观其行，是认识一个人最好的方法”。
A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Funded partly by firms and companies, the charity places top graduates in schools serving low-income communities for at least two years, knowing full well that many of them will leave the profession at the end of this period.
Novel biosensing methodologies for ultrasensitive detection of viruses
Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
ACE2 as a potential therapeutic target for pandemic COVID-19
But the struggle for white identity is not just a political problem; it is about the “deep story” of feeling stuck while others move forward.
Diagnostic technologies for COVID-19: a review
ESCP Europe and MIT Sloan School of Management in the US also performed well. Both schools climbed five places into third and fifth place respectively.
Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
10. 迪皮卡-帕度柯妮 1000万美元
An overview of key potential therapeutic strategies for combat in the COVID-19 battle
“One employee threw a cup of coffee and walked out.”
Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
6. "How I Met Your Mother" (3.0 million)
Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
'What I was trying to do was wrap myself in his mantle and write a book that would be worthy of him.'
In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
To make sure the plan goes through, the central government must reinforce the plan to co-ordinate basic pension, enhance enterprise annuity and manage personal accounts properly, Yang said.
Antiviral drug discovery: broad-spectrum drugs from nature
Influenza neuraminidase: A druggable target for natural products
It is the continual shrinkage of components that have unleashed the explosion of computing power and enabled these gadgets to be accessible to people across the world.
都不是。1772年,一场空前的危机击中了阿姆斯特丹：一家受人尊敬的荷兰投资银团对不列颠东印度公司(British East India Company)股票的投资变成了一场灾难。
Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
Captain America: Civil War will hit theatres May 6, 2016. Who's side are you on?
The role of biosensors in the detection of emerging infectious diseases
Quantitative determination of mechanical stability in the novel coronavirus spike protein
The refugees have streamed into Greece, Bulgaria, Italy, Spain, Malta and Cyprus during 2015, with a huge majority -- over 800,000 -- arriving by sea in Greece. About 3,600 died or disappeared trying to make the perilous Mediterranean Sea crossing between North Africa and Italy.
Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
4. No talking during the game, wait for half-time or end of the game.
Inside larger technology companies, female employees will be hoping for signs of change in pay and promotions — but will also be on guard, as a men’s rights backlash brews in some corners of Silicon Valley.
8. Jessica Gomes
MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
As early as 2008, wearable technology—which can range in anything from measuring your heart rate to curating music based on your mood—has been touted as the next big moment in consumer electronics.
More than 430,000 students from 1,767 universities in 31 provinces, municipalities and autonomous regions across China were surveyed. Of the respondents, 89.2% had considered starting a business, with 18.2% reporting firm intentions to do so.
Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Not a lot of Bond villains get their own theme song, but Christopher Lee's assassin from The Man with the Golden Gun gets a flashy, catchy, groovy tune that makes him seem cool as hell. (And of course, he is.) Lulu completely sells the awesomeness of the villain Scaramanga, and although the song may seem almost ridiculously upbeat today, it only adds to the charm.
Inhibition of SARS coronavirus helicase by bismuth complexes
The Veterans Day holiday, which pays tribute to all men and women who have served in the U.S. military, dates back to 1919, when President Woodrow Wilson proclaimed November 11 as Armistice Day to celebrate the end of fighting exactly one year earlier in World War One - "the war to end all wars" - between Germany and the allied nations of Britain, France and the United States. The armistice famously went into effect at "the eleventh hour of the eleventh day of the eleventh month."
2. American shale.By the end of 2014, the U.S. was producing more than 9 million barrels of oil per day, an 80 percent increase from 2007. That output went a long way to creating a glut of oil, which helped send oil prices to the dumps in 2014. Having collectively shot themselves in the foot, the big question is how affected U.S. drillers will be by sub-$60 WTI. Rig counts continue to fall, spending is being slashed, but output has so far been stable. Whether the industry can maintain output given today’s prices or production begins to fall will have an enormous impact on international supplies, and as a result, prices.
Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
She emotes with some of Pink's husky attitude and some of Sia's theatrical so-over-it-ness, but she's a warmer singer than either, whether shrugging off a lover on the self-explanatory "IDGAF" or matching Miguel's intensity on the steamy "Lost in Your Light."
A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
In the field of the best 85 business schools in Europe, HEC Paris remains in second place behind LBS, while Insead, the international school based in Fontainebleau, France, climbs two places to third.
Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.
Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.
Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
“What Happened, Miss Simone?” (Liz Garbus)
China has overtaken the United States to become Germany's top trading market in 2016 for the first time, according to data collected by the Association of German Chambers of Commerce and Industry (DIHK).
Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
12. “The Kindergarten Teacher” (Nadav Lapid)
“LBS has a great student body, very diverse in terms of nationality, competitive and intelligent,” commented one American graduate from the class of 2012. “It also gave me the opportunity to study in the US [on exchange] without having to do a purely US-focused American MBA.”
Dachis says: The end of year iPhone 5 and iPad Mini releases overcame early controversies in overseas manufacturing and any lingering effects from the death of Steve Jobs to make Apple the biggest mover of the year.
A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
The government is keen to encourage lending to small and medium-sized borrowers, many of whom do not have credit histories. Analysts estimate the number of Chinese consumers who are financially active but without access to credit to be 500m.
Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
用户在百度搜索平台上最常点阅的新闻事件是，为纪念二战胜利70周年于9月3日在北京举行的阅兵仪式。在此次庆祝活动中，上万名军人接受了现任国家主席习近平、前任主席胡锦涛和江泽民，以及多位外国领导人的检阅，其中包括俄罗斯总统弗拉基米尔·V·普京(Vladimir V. Putin)。
Had the North Koreans not set off another nuclear test at the weekend the big story this week on the Korean peninsula might have been the Trump administration’s odd timing in announcing its plans to pull out of a trade deal with Seoul.
The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
James Bond Themes 10. "Diamonds Are Forever" by Shirley Bassey
其他人将想方设法利用技术来帮助人们减少上网时间。谷歌(Google)前雇员特里斯坦哈里斯(Tristan Harris)发起的“时光莫虚度”(Time Well Spent)运动正在吸引人气，该运动鼓励设计者理解他们所控制的微妙的心理力量，以解决其所称的“数字注意力危机”。据Recode报道，曾经在Pinterest和Facebook工作的蒂姆肯德尔(Tim Kendall)，计划成立一家专注于对抗设备上瘾的初创公司。
Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Several South Korea-linked entities have already felt Beijing’s wrath in response to the Thaad plans. Chinese state news agency Xinhua last month issued a stark warning to Lotte, one of South Korea’s biggest companies, for giving up land on which the Thaad platform will be hosted.
The programme entered the ranking in second place in 2006 and was ranked top in 2008.
Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
位于芬兰赫尔辛基的开发商Remedy Entertainment通过之前的作品《英雄本色》（Max Payne）和《心灵杀手》（Alan Wake）模糊了好莱坞和游戏之间的界限。如今，这家工作室将次世代的图像技术与紧张气氛和电视剧剧本结合了起来。故事设置在Riverport大学城，玩家将控制杰克o乔伊斯和贝斯o怀尔德。这两人原本是普通人，但在一次导致时间裂缝的意外中，他们获得了操纵时间的超能力。在游戏过程中，时间体系会随时崩溃，导致环境中的时间暂停、断续、倒流和冻结。玩家在游戏中会与帝王联盟（Monarch Corporation）展开对抗，喜欢《英雄本色》中子弹时刻的玩家，可以在放大时间因素的枪战中寻找新的战略。除了虚拟的故事情节，游戏还采用了定制的实景真人叙事模式，根据玩家的不同选择将产生不同的后果。
Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Pyongyang, which refers to Park as "human scum' has long condemned the balloon launches and in recen onths has stepped up its demands for Seoul to ban them.
Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
The American Film Institute has picked its 10 best movies and TV shows of the year. The titles, presented in alphabetical order, are works AFI's juries have determined advance the art of the moving image, enhance the cultural heritage of America's art form, inspire audiences and artists and make a mark on American society.
The renewal of the 70-year term of land-use rights by urban-dwelling owners will be no problem. No application needs to be filed, there will be no preset conditions and it will not affect any deal being made over the property.
We will work to ensure that our people have access to equitable and quality education.
The leadership changes across the industry will be of particular interest to female consulting professionals, given none of these firms have ever been run by a woman. Consulting firms are vocal proponents of the business case for improved gender diversity at the top of large companies. It will be interesting to see if any of them decide to practice what they preach.
Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Think you’ve had some bad job interviews this year? This survey is guaranteed tcheer you up (unless you happen tbe part of it). When staffing firm OfficeTeam asked 600 managers across North America tdescribe the most embarrassing interview blunders they had seen in 2014, here’s what they said.
The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
For Maddie Ziegler, from Pennsylvania, life couldn't be more different.
Halloween is just a few days away. Which means, if you haven’t gotten your costume or decorations sorted out yet, you might want to start doing that pretty soon.
Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
5. How to play poker
Texas was one of the first states to emerge from the recession and it continues to attract companies on the basis of its low tax burden, predictable regulatory environment and skilled labor force. Texas employment is expected to expand 3% annually through 2017, according to Moody’s. (Arizona’s forecasted rate is a microscopic 0.04% better). Texas has attracted a lot of attention from California companies and Governor Rick Perry has not been shy about contrasting the business climates of the two states. California firms EBay and Electronic Arts have both chosen Texas for large expansions in recent years. Austin has been a hotbed of activity this year with Accenture
Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.
Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.
Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.
Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
A modular microarray imaging system for highly specific COVID-19 antibody testing
Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
The regulator said that “faced with a complex and volatile market environment,” funds had realised gains of only Rmb294.5bn in the first half, a drop of 42.3 per cent.
Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.
Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
China's booming cyberstar economy has gone through three stages -- the first based on text, then text and images, and now video thanks to the availability of broadband networks.
A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
In 2017, his 14th season in the league, LeBron James averaged a career high in assists and rebounds. In the first two months of 2017-18, he's averaging a career high in 3-point percentage, but that's been talked about and dissected; it's been written about extensively.
An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.
Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
A facile assay for rapid detection of COVID-19 antibodies
Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
American brands such as Chipotle, Texas Instruments and General Dynamics are on the list for the first time.
Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
In interviews, everyone works well with others, and everyone learns quickly. Please tell me something else.
Colliding Neutron Stars
Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.
Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Anti-HIV drug repurposing against SARS-CoV-2
6. Gene therapy comes good.
Length-scale dependence of protein hydration-shell density
5.3-D Printed Ears
Capsized ship righted
Global emissions of greenhouse gases jumped 2.3 percent in 2013 to record levels, scientists reported Sunday, in the latest indication that the world remains far off track in its efforts to control global warming.
High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Human bodies are frail, easily damaged packages full of parts that can never fully come back once lost. Luckily, researchers worldwide are working on replacing every bit of the body to make us all cyborgs.
A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
'Her,' which was written and directed by Spike Jonze, takes romance into the virtual realm, and its hero on a gently crazed journey of genuine passion. Joaquin Phoenix is the poignantly lonely guy who falls in love with his smartphone's new operating system. The basic conceit is a fragile one, but it's beautifully and bravely developed, as well as elegantly photographed by Hoyte Van Hoytema, with perfectly calibrated performances by Mr. Phoenix, Amy Adams and Scarlett Johansson, who is that system's voice and soul.
Elspeth Cheung, head of BrandZ valuation at Millward Brown, says: “The top 10 used to be dominated by consumer goods. This year, it’s technology.”
About this collection
China saw its population grow last year, along with an improved male-female ratio and the level of education, according to a survey from the National Bureau of Statistics that was released on last Wednesday.
This is not to take anything away from Tesla, which has demonstrated that it can create and manufacture a complex and sophisticated product with demonstrated customer appeal. But its own internal forecasts, as well as the swelling of its share price, are based on the expectation that the future will unspool in an orderly fashion identical to the recent past. That’s a dangerous assumption to make – for several reasons: